Novel microtubule-targeting agents – the epothilones
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چکیده
منابع مشابه
Novel microtubule-targeting agents – the epothilones
Epothilones are a new class of antimicrotubule agents currently in clinical trials. Their chemical structures are distinct from taxanes and are more amenable to synthetic modification. Six epothilones have been studied in preclinical and clinical trials: patupilone (epothilone B), ixabepilone (BMS247550), BMS 310705, sagopilone (ZK-EPO), KOS-862 (epothilone D), and KOS-1584. In vitro data have ...
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ژورنال
عنوان ژورنال: Biologics: Targets & Therapy
سال: 2008
ISSN: 1177-5475
DOI: 10.2147/btt.s3487